Cart
sales@molnova.com
Dronedarone hydrochloride
CAS No. 141625-93-6
Dronedarone hydrochloride ( SR-33589 hydrochloride )
Catalog No. M11733 CAS No. 141625-93-6
A multichannel blocker agent that has antiarrhythmic activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 29 | In Stock |
|
| 10MG | 43 | In Stock |
|
| 25MG | 79 | In Stock |
|
| 50MG | 124 | In Stock |
|
| 100MG | 178 | In Stock |
|
| 200MG | 266 | In Stock |
|
| 500MG | 448 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameDronedarone hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionA multichannel blocker agent that has antiarrhythmic activity.
-
DescriptionA multichannel blocker agent that has antiarrhythmic activity; reduces the late sustained K(+) current, I(K) (or Isus) with EC50 of 0.85 uM in postmyocardial infarcted (PMI) rats; reduces significantly the incidence of ventricular fibrillation (VF) in rats; mainly used for treatment of cardiac arrhythmias.Heart Arrhythmia Approved
-
SynonymsSR-33589 hydrochloride
-
PathwayCell Cycle/DNA Damage
-
TargetPotassium Channel
-
RecptorAdrenergicReceptor;CalciumChannel;PotassiumChannel;SodiumChannel
-
Research AreaCardiovascular Disease
-
IndicationHeart Arrhythmia
Chemical Information
-
CAS Number141625-93-6
-
Formula Weight593.22
-
Molecular FormulaC31H45ClN2O5S
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESCl.CCCCN(CCCC)CCCOC1=CC=C(C=C1)C(=O)C1=C(CCCC)OC2=C1C=C(NS(C)(=O)=O)C=C2
-
Chemical NameMethanesulfonamide, N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-5-benzofuranyl]-, hydrochloride (1:1)
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Aimond F, et al. J Pharmacol Exp Ther. 2000 Jan;292(1):415-24.
2. Sun W, et al. Circulation. 1999 Nov 30;100(22):2276-81.
3. Manakshe G, et al. Indian Heart J. 2012 Mar-Apr;64(2):182-6.
2. Sun W, et al. Circulation. 1999 Nov 30;100(22):2276-81.
3. Manakshe G, et al. Indian Heart J. 2012 Mar-Apr;64(2):182-6.
molnova catalog
related products
-
PD-118057
A potent, selective hERG potassium channel (Kv11.1) activator that increases peak tail hERG current of 111.1% at 10 uM in HEK293 cells.
-
NS19504
NS19504 is an activator of Ca2+-activated K+ channel with EC50 of 11.0 μM. NS19504 shows relaxing effect on bladder smooth muscle spontaneous phasic contractions.
-
NS8593 hydrochloride
NS8593 hydrochloride is a potent and selective inhibitor of small conductance Ca2+-activated K+ channels (SK channels) .
