Dronedarone hydrochloride

CAS No. 141625-93-6

Dronedarone hydrochloride ( SR-33589 hydrochloride )

Catalog No. M11733 CAS No. 141625-93-6

A multichannel blocker agent that has antiarrhythmic activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 29 In Stock
10MG 43 In Stock
25MG 79 In Stock
50MG 124 In Stock
100MG 178 In Stock
200MG 266 In Stock
500MG 448 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Dronedarone hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    A multichannel blocker agent that has antiarrhythmic activity.
  • Description
    A multichannel blocker agent that has antiarrhythmic activity; reduces the late sustained K(+) current, I(K) (or Isus) with EC50 of 0.85 uM in postmyocardial infarcted (PMI) rats; reduces significantly the incidence of ventricular fibrillation (VF) in rats; mainly used for treatment of cardiac arrhythmias.Heart Arrhythmia Approved
  • Synonyms
    SR-33589 hydrochloride
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Potassium Channel
  • Recptor
    AdrenergicReceptor;CalciumChannel;PotassiumChannel;SodiumChannel
  • Research Area
    Cardiovascular Disease
  • Indication
    Heart Arrhythmia

Chemical Information

  • CAS Number
    141625-93-6
  • Formula Weight
    593.22
  • Molecular Formula
    C31H45ClN2O5S
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    Cl.CCCCN(CCCC)CCCOC1=CC=C(C=C1)C(=O)C1=C(CCCC)OC2=C1C=C(NS(C)(=O)=O)C=C2
  • Chemical Name
    Methanesulfonamide, N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-5-benzofuranyl]-, hydrochloride (1:1)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Aimond F, et al. J Pharmacol Exp Ther. 2000 Jan;292(1):415-24.
2. Sun W, et al. Circulation. 1999 Nov 30;100(22):2276-81.
3. Manakshe G, et al. Indian Heart J. 2012 Mar-Apr;64(2):182-6.
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